The stability of microencapsulated fish oil prepared with 2 production processes, spray granulation (SG) and SG followed by film coating (SG-FC) using a fluid bed equipment, was investigated. In the 1st process, 3 types of fish oil used were based on the ratios of eicosapentaenoic acid (EPA) and docosahexaenoic acid (DHA) (10/50, 33/22, and 18/12). Each type was emulsified with soluble soybean polysaccharide (SSPS) and maltodextrin to produce 25% oil powders. In the 2nd process, 15% film coating of hydroxypropyl betacyclodextrin (HPBCD) was applied to the granules from the 1st process. The powder stability against oxidation was examined by measurement of peroxide values (PV) and headspace propanal after storage at room temperature and at 3 to 4 degrees C for 6 wk. Uncoated powder containing the lowest concentration of PUFA (18/12) was found to be stable during storage at room temperature with maximum PV of 3.98 +/- 0.001 meq/kg oil. The PV increased sharply for uncoated powder with higher concentration of omega-3 (in 33/22 and 10/50 fish oils) after 3 wk storage. The PVs were in agreement with the concentration of propanal, and these 2 parameters remained constant for most of the uncoated powders stored at low temperature. Unexpectedly, the outcomes showed that the coated powders had lower stability than uncoated powders as indicated by higher initial PVs; more hydroperoxides were detected as well as increasing propanal concentration. The investigation suggests that the film-coating by HPBCD ineffectively protected fish oil as the coating process might have induced further oxidation; however, SG is a good method for producing fish oil powder and to protect it from oxidation because of the "onion skin" structure of granules produced in this process.

中文翻译：

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通过喷雾造粒和流化床薄膜包衣微胶囊化鱼油

研究了使用流化床设备通过喷雾造粒 (SG) 和 SG 后薄膜包衣 (SG-FC) 2 种生产工艺制备的微胶囊鱼油的稳定性。在第一道工序中，根据二十碳五烯酸 (EPA) 和二十二碳六烯酸 (DHA) 的比例（10/50、33/22 和 18/12），使用了 3 种类型的鱼油。每种类型都用可溶性大豆多糖 (SSPS) 和麦芽糊精进行乳化，以产生 25% 的油粉。在第二道工序中，将 15% 的羟丙基 β 环糊精 (HPBCD) 薄膜包衣应用于第一道工序的颗粒。在室温和 3 至 4 摄氏度下储存 6 周后，通过测量过氧化值 (PV) 和顶空丙醛来检查粉末对氧化的稳定性。发现含有最低浓度 PUFA (18/12) 的未包衣粉末在室温下储存期间是稳定的，最大 PV 为 3.98 +/- 0.001 meq/kg 油。在储存 3 周后，具有更高浓度 omega-3（在 33/22 和 10/50 鱼油中）的未涂层粉末的 PV 急剧增加。PVs 与丙醛的浓度一致，对于在低温下储存的大多数未涂覆粉末，这两个参数保持不变。出乎意料的是，结果表明涂层粉末的稳定性低于未涂层粉末，如较高的初始 PV 所示；检测到更多的氢过氧化物以及增加的丙醛浓度。调查表明，HPBCD 的薄膜包衣不能有效地保护鱼油，因为包衣过程可能会引起进一步的氧化；然而，