With a minimum of chemistry, we developed a tool based on functionalized colloidal probes that mimic the presence of adjacent cells detecting the presence of E-cadherins on the cell surface. The specificity and dynamic strength of the peptide-E-cadherin interaction can be read out demonstrating the potential for a label-free screening of cell surfaces.

中文翻译：

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附着在胶体探针上的 HAV 肽可准确检测活细胞上显示的 E-钙粘蛋白

我们用最少的化学知识开发了一种基于功能化胶体探针的工具，该工具可以模拟相邻细胞的存在，检测细胞表面上 E-钙粘蛋白的存在。可以读出肽-E-钙粘蛋白相互作用的特异性和动态强度，证明了细胞表面无标记筛选的潜力。